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The Best Weed Killers - 2022

Last updated on April 20, 2022

We looked at the top 10 Weed Killers and dug through the reviews from 40 of the most popular review sites including and more. The result is a ranking of the best Weed Killers.

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Our Picks For The Top Weed Killers

Show Contents
Our Take
Experts Included
Pros
Cons
  Top Pick

Ortho GroundClear Weed Killer

Don't Waste Your Money Seal of Approval

Ortho

GroundClear Weed Killer

Overall Take

Concentrated, Fast-ActingUse this concentrate with a tank sprayer, and you won’t have to worry about undesirable vegetation for months to come!

Experts Included
DWYM Outdoor and Garden Experts plus Bumper Crop Times, Rural Living, This Old House and 1 more. Along with user reviews from Amazon.
Pros
" If you use Ortho Ground Clear, you will see the results in just a few hours."
Cons
"On average, homeowners noticed the weed killer worked for a maximum of six months."
  Runner Up

Spectracide AccuShot Sprayer Weed & Grass Killer2

Spectracide

AccuShot Sprayer Weed & Grass Killer2

Overall Take

Hits the RootsThis quick-working product works effectively, leaving your yard all the better!

Experts Included
DWYM Outdoor and Garden Experts plus This Old House, Gardening Dream, Weed Killer Guide and 1 more. Along with user reviews from Amazon.
Pros
" This concentrated weed killer produces visual results within three hours of application on driveways, fences, flower beds, shrubs, and other surfaces."
Cons
"Only lasts for five months"
  We Also Like

Compare-N-Save Concentrate Herbicide Weed Killer

Compare-N-Save

Concentrate Herbicide Weed Killer

Overall Take

A Huge SupplyThis weed killer provides a lot of coverage for a very reasonable price!

Experts Included
DWYM Outdoor and Garden Experts plus Rural Living, Weed Killer Guide, Garden Synthesis, Top Tillers. Along with user reviews from Amazon.
Pros
" Fortunately, this concentrate is easy to mix with water on your own, compared to pre-mixed brands."
Cons
"Results are not that immediate – It takes a bit longer for it to produce its results when compared to the others."
  Strong Contender

The Andersons Barricade Pre-Emergent Weed Killer

The Andersons

Barricade Pre-Emergent Weed Killer

Overall Take

What the Pros UseThis product is the one professionals turn to for weed prevention.

Experts Included
DWYM Outdoor and Garden Experts plus Bob Vila, Garden Helpful, The Yard and Garden, Yard & Garden Guru. Along with user reviews from Amazon.
Pros
" Prevents more than 30 types of grass and weeds"
Cons
"Must be watered in to facilitate activation"
Don't just take for granted what one reviewer says. Along with our own experts, DWYM analyzes the top expert reviews of the leading products and generates a score you can actually trust.
17

Products Considered

We identified the majority of the weed killers available to purchase.
10

Products Analyzed

We then selected the leading and most popular products for our team to review.

View All Product Rankings

40

Expert Reviews Included

In addition to our expert reviews, we also incorporate feedback and analysis of some of the most respected sources including: Good Housekeeping, Bob Vila, Your Best Digs, Family Handyman, This Old House.

36,053

User Opinions Analyzed

We also incorporate user reviews from the leading retailers including

Our experts reviewed the top 10 Weed Killers and also dug through the reviews from 40 of the most popular review sites including and more. The result is a ranking of the best of the best Weed Killers.

DWYM is your trusted roduct review source. Our team reviews thousands of product reviews from the trusted top experts and combines them into one easy-to-understand score. Learn more.

Don't Waste Your Money Seal of Approval
Look for the DWYM seal for products that are the best in their category.

The Best Overall

Ortho GroundClear Weed Killer


Our Expert Score

0.0
4 expert reviews

User Summarized Score

8.8
5,877 user reviews

Our Take

Ortho GroundClear Concentrate is the industry standard for effective weed killing; a single application or the fast-acting formula prevents regrowth for as long as a year. It can get rid of the most stubborn, ugly weeds.

What other experts liked

Does a good job of killing weeds
- Everything Backyard
If you use Ortho Ground Clear, you will see the results in just a few hours.
- Bumper Crop Times
It dries quickly after application, and the chemical smell will disperse after 20 minutes.
- Rural Living
This spray starts working immediately on all types of weeds and grasses.
- This Old House

What other experts didn't like

Will kill grass also
- Everything Backyard
The only downside (and distinction) of the Ground Clear products is that they contain imazapyr, which destroys plants’ roots. Therefore, if you use them where other (beneficial) plants thrive, the herbicide will easily destroy them as well.
- Bumper Crop Times
On average, homeowners noticed the weed killer worked for a maximum of six months.
- Rural Living

The Best Bang For Your Buck

Spectracide AccuShot Sprayer Weed & Grass Killer2

Our Expert Score

0.0
4 expert reviews

User Summarized Score

9.0
864 user reviews

Our Take

At just the right price for 1.33 gallons, this effective weed killer attacks invasive weeds and grasses on your property. Its AccuShot applicator provides precise application; children and pets can return to the area after it has been watered and has dried.

What other experts liked

This concentrated weed killer produces visual results within three hours of application on driveways, fences, flower beds, shrubs, and other surfaces.
- This Old House
Visible results can be seen in just 3 hours after application.
- Everything Backyard
Rain ready in a short period of time
- Gardening Dream
Capable of killing more than a hundred weed and grass species
- Weed Killer Guide

What other experts didn't like

Will need a sprayer to apply
- Everything Backyard
Only lasts for five months
- Gardening Dream
Not ideal for spot weed treatments done in lawns
- Weed Killer Guide

Overall Product Rankings

1. Ortho GroundClear Weed Killer

Overall Score: 9.5
Reviews Included: 5

2. Spectracide AccuShot Sprayer Weed & Grass Killer2

Overall Score: 9.4
Reviews Included: 5

3. Compare-N-Save Concentrate Herbicide Weed Killer

Overall Score: 9.2
Reviews Included: 5

4. The Andersons Barricade Pre-Emergent Weed Killer

Overall Score: 9.0
Reviews Included: 5

5. Natural Armor Glyphosate-Free Concentrated Weed Killer

Overall Score: 8.9
Reviews Included: 5

6. RM43 Total Vegetation Control Weed Killer

Overall Score: 8.7
Reviews Included: 5

7. Doctor Kirchner Natural Weed Killer

Overall Score: 8.6
Reviews Included: 5

8. Roundup Extended Control Ready-To-Use Weed Killer

Overall Score: 8.6
Reviews Included: 5

9. Southern Ag 2,4-D Amine Weed Killer

Overall Score: 8.5
Reviews Included: 5

10. Hi-Yield Killzall Concentrated Weed Killer

Overall Score: 8.4
Reviews Included: 5

Our Weed Killer Findings


Ortho GroundClear Weed Killer

What We Liked: Ortho GroundClear Concentrate is the industry standard for effective weed killing; a single application or the fast-acting formula prevents regrowth for as long as a year. It can get rid of the most stubborn, ugly weeds.


Spectracide AccuShot Sprayer Weed & Grass Killer2

What We Liked: At just the right price for 1.33 gallons, this effective weed killer attacks invasive weeds and grasses on your property. Its AccuShot applicator provides precise application; children and pets can return to the area after it has been watered and has dried.


Compare-N-Save Concentrate Herbicide Weed Killer

What We Liked: This potent weed killer is made with 41% glyphosate and works on most annual and perennial weeds and grasses. The concentrate inside the container makes up to 210 gallons of spray, covering up to 630,000 square feet.


The Andersons Barricade Pre-Emergent Weed Killer

What We Liked: This professional-grade weed killer is made for you to use in the early spring and fall. It combats pre-emergent weed growth and prevents more than 30 kinds of broadleaf weeds and grasses.


Natural Armor Glyphosate-Free Concentrated Weed Killer

What We Liked: Here’s a concentrated, all-natural weed killer that contains no glyphosate. It is people- and pet-friendly and kills more than 250 kinds of unwanted weeds and grasses. It will work for cleaning up your flower beds, trees, shrubs, edging, foundations and other outdoor areas.

Our Weed Killer Buying Guide

Also known as herbicides, weed killers are chemicals applied to control and eliminate unwanted vegetation like weeds and crabgrass. They can inhibit a weed’s cell division or photosynthesis and disrupt its amino acid production.

Other weed killers mimic natural plant growth hormones and cause deformities. You can spray them onto foliage or soils, and one of the best-known weed killer chemicals is glyphosate. This chemical is an amino acid disrupter with a broad spectrum and low toxicity to animals.

Chemical-based weed killers are more common, but natural herbicides can also work pretty well. Some contain citrus oil and vinegar, which causes weeds to dry out, curl up and die. These are good for people who have pets and small children, but the chemical counterparts can be just as safe when applied according to the label directions. The best ones work in 24 hours or less, so it’s best to keep everyone away from the area for the time specified on the product label.

Some retailers sell liquid herbicides in smaller, ready-to-use containers or in concentrate form; these methods can be cost-saving. You must apply granular weed control products with spreaders, which is easy to do if you need to cover a whole lawn.

Pre-emergent weed killers are not referred to as herbicides; they are weed preventers and attack sprouting weed seedlings before they emerge from the ground. You’ll want to use these in the spring and fall. Herbicides, which are known as post-emergent weed killers, control existing weeds instead.

DWYM Fun Fact

Believe it or not, there are some beneficial weeds out there. Some provide critical ecosystem functions, like restoring and protecting degraded and exposed soils. Others offer habitats for beneficial organisms and can control insects; certain ones also provide food or fodder.

Here are a few examples: dandelion greens are full of calcium, and you can use yarrow as a digestive aid or to treat fever. Then there’s chickweed, which is high in vitamin C and has vitamins A, B and D, plus calcium, iron and potassium. This chickweed can be made into a salve to treat burns, cuts, rashes, eczema and acne.

The Weed Killer Tips and Advice

  • Weedkiller and preventer granules can be combined with dry fertilizer and spread simultaneously. This method is an excellent way to kill two birds (and many weeds) with one stone.
  • Be careful with broad-spectrum weed killers because they are non-selective and may kill desirable plants and grasses. The labels usually specify which weeds the products work on.
  • If you are overrun with a tough weed like nutsedge, choose a selective weed killer that lists the particular one on the label.
  • Herbicides don’t have expiration dates and can last for up to five years. Shake well before using and follow the label directions carefully.
  • Keep the weed container lid on tightly and away from high heat, sunlight, children and pets.

About The Author

Danielle Smyth 

Danielle Smyth is a writer and content marketing expert based in New York. She has been writing on business and finance, home and garden, DIY, travel and tourism, and a variety of other topics for over a decade, and she holds a Master of Science in Publishing from Pace University. Danielle loves working on product reviews and helping others find the highest quality items and the best values. An avid gardener and home improvement fanatic, she is always looking for new products to make life easier.